BIRTH OF THE GENOME BASED ECONOMY - CHURCHILL CLUB, Jan 22, 2009 (YouTube)
"Technology breakthroughs are making DNA sequencing faster and cheaper than ever. In its top ten list of 2008 scientific breakthroughs that broke through with the potential for lasting impact, Science magazine included technology that has blown the doors off genome sequencing. In Nature magazines list of the top news stories of 2008, "Personal genomics goes mainstream" came in second. With the cost of DNA sequencing plummeting, the emergence of "molecular sequencing" platforms has forever changed the field of genetics.
A new paradigm appears on the horizon. Personal genome information will be used not just for health maintenance, disease diagnosis, and treatment, but will also be the foundation for lifestyle applications from shopping for food, to buying cosmetics, to assessing ones environment and making choices about fabrics, places - even friends.
This panel of Silicon Valley players and innovators of new business models examines the dynamic business and investment opportunities as well as the risks, global competition, regulatory and legal challenges, new individual contributor roles, and leading alliances emerging from Silicon Valley and beyond.
Silicon Valley changed the world as the driving force in the development of computers and the internet. Could we play a similar role in advancing a genome-based economy?"
Linda Avey, Founder, 23andMe
David Medina, HP Chief Technologist, Worldwide Health & Life Sciences
Karoly Nikolich., Dievini Hopp Biotech Holding, CEO of Amnestix
Andras Pellionisz, Founder, International Hologenomics Society and HolGenTech
Dietrich Stephan, Founder, Navigenics, founder of Amnestix
Phyllis Whiteley, Mohr-Davidow Ventures
Karen Tucker, CEO Churchill Club - A Churchill Club event Thursday January 22, 2009, Palo Alto, CA,
Suzanne Matick, Principal,, Gutenberg Communications: Gutenberg, Los Gatos Office
Some feedback on the event to Churchill Club CEO Karen Tucker:
Thanks for giving me the opportunity to attend the meeting. Event was informative about Genomics and Personalized Medicines. Speakers gave a lot of different angles to the topic. I was particularly impressed at the ease with which scientific information was passed on for lay person's understanding. Moderator gave a lot of insight to the topic as well which added value to information speakers' provided. From an educator's point of view, this event was helpful to stay updated with Genomics and Personalized medicine. This information will be included in the developing curriculum for MVROP. It is important for industry and academics to stay connected. This will help in workforce needs and appropriate curriculum to be taught for the same. It would be great if events like this can also include dialogue of possible Industry Academic Partnerships to improve occupational training programs.
--Mission Valley ROP Biotech Instructor
Thanks again for the invitation. I really enjoyed the event. As far as the concepts I came away with:
The personal genomic revolution has the potential to be huge and impact just about every aspect of our society from medicine to lifestyles to marketing for products and services targeted our genomes.
What it will take:
1. Hardware that can process enormous amounts of information quickly
2. Software that can store, access, update new information and correlate
3. Volunteer populations to develop a data base
4. Doctors trained to use the new information proactively
5. Consumers who are educated and supported.
Because the timeline is anticipated at 10-15 years, it is important that our students be educated about their options when considering potential careers as well as informed choices.
Crystal Springs Upland School
This was a terrific and thought-provoking panel discussion. It helped that I had heard two scientists from 23 and Me and Navigenics speak about their companies, particularly the underlying science, at a previous event. I felt that the panelists were very grounded in some realities as they looked to the future. These included:
-- the very important need for education in many areas: electronic medical records (and doctors needing to embrace the technology); genomics (medical profession as well as the health consumer); bioinformatics (how to store, organize, access, visualize, interpret AND use the data by professionals; how to simplify for lay understanding); metabolomics/nutrition (the importance of personal metabolism and interactions of foods, supplements, drugs, etc.); students and their teachers (for future employees, entrepreneurs, and informed customers);
-- the very important need for continued development of electronic storage, organization, and information access; also, how to present massive data in a visual form to improve conceptual and big picture understanding;
-- the continued importance of basic research, which is the foundation for the applications;
-- the intriguing use of your personal genetic/metabolic profile "on a stick" - to take with you to the doctor's office; to the grocery store to pop into a small box near a food to find out if that is a food "good" for YOU!
-- the respect that people will need easy access to dependable and affordable counseling to understand their genetics and the implications of "risk" vs. actual disease;
-- the understanding that ethical issues will be a constant companion to development on all these fronts.
Thank you for the opportunity to attend! Biology Department, Stanford University
It was an honor to attend this event. I learned so much from the speakers as well as the industry professionals seated at my table. I didn't know what to expect as I've been out of the biotech industry for many years. Everything I learned was new for me. The concept of a genomic economy based on access of personal genomes fascinated me. I still think about the ideas shared that night and wonder what the future will look like with these technologies and information. I felt like I was the only one in the room listening to these ideas for the first time. I thought I stepped into a science fiction movie. I was impressed at how fast this field has evolved since the days of sequencing the genome, by hand, using polyacrylamide gels.
I gained a better perspective of the current science and technologies and the collaborations across disciplines necessary to make it happen. As a science teacher, I came away with a sense that we are not preparing our students for what's to come in the field of genomics. I shared what I learned at the Churchill Club event with my students. They were fascinated. They still talk about how cool it would be to have access to their personal genome. To see the spark in their eyes regarding this topic really impressed me. I have to incorporate more biotechnolgy into my lesson plans. Thank goodness for all the support from people like Katy Korsemeyer and the local colleges and biotech companies. We are truly blessed in Silicon Valley. 8th grade science teacher
Thank you again for giving us this opportunity. I enjoyed listening to the panel's various points of view, each had a focus based on their experience and work, acknowledging the ethical and unknown consequences of this leading edge science and their hopes and visions for the future. The educators who were able to attend valued this opportunity and can bring such an experience back into the classroom.
It was a great event- looking forward to more of such events. Great, high quality panel.
Excellent event - I thoroughly enjoyed it and learned a great deal about the potential for the future in this area.
Lots of buzzwords and ideas that I have seen before and that have been around in the life sciences space for a long time. Herceptin was launched 10 years ago and nothing in the area of "personalized medicine" has happened since. Found it to be too IT heavy, too optimistic that problems could be solved "if only we had more data." No one on the panel had a true healthcare (provider, payor, public health, government) background. Healthcare is fundamentally not a problem that will be solved with more data.
Great event, next time more audience involvement earlier in the process
Excellent program. Very thought provoking.
HomePage of GenomeBasedEconomy
Churchill Club: Personal Genome Computing Heralds the Genome-Based-Economy (by Susan Matick, Principal, Gutenberg Communications))
Massachusetts Governor D. Patrick says the "Genome Based Economy" is a "Wonderful Idea"
Forbes (Ed Sperling) on International HoloGenomics Society
DNA algorithm predicts human behaviour [Genome Based Economy taking off in New Zealand...]
Safeway gives $685,000 to TGen for breast cancer research
New York Times (Nicholas Wade) From One Genome, Many Types of Cells. But How? ["The Principle of Recursive Genome Function"]
Ray Kurzweil: “The human brain is simpler than it appears…it’s basically just a recursive probabilistic fractal.”
Genome Based Economy is Here - within weeks, not years...
Sue Siegel (Mohr Davidow Venture) YouTube - endorses Genome Based Economy on Churchill Club
Regulatin' Genome YouTube - Who will make Genome Based Economy Happen - The Genome Based Generation
Play Regulatin' Genes YouTube
The 21st Century "Genome Based Generation" throws old papers away at their 7th second, when the first script appears. Proteins recursing to the DNA to regulate genome function used to be, for half a Century something that "never happens" (Crick, 1956; "The Central Dogma of Molecular Biology"). A paper in June 14, 2008 and a Google Tech YouTube on October 30, 2008 blew not one, but two "obsolete axioms" away (also, the "Junk DNA misnomer" is gone - minus a handful of hold-out "old schoolers"). For the Generation making the Genome Based Economy happen, (proteins) "regulatin' genes" is the fresh start.