
Kishore R. Sakharkar
Computational Biologist,
Medical Faculty, National University of Singapore
EDUCATION
Ph.D. (Computational Biology and Drug Discovery),
Faculty of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
M.Tech, (Computer Science), BITS, Pilani, India.
PROFESSIONAL EXPERIENCE (1983-2005):
2005 onwards - NUMI, Research Scientist, National University of Singapore, Singapore.
2003- 2005, Project Manager, Computational Biology Group, BioInformaics Institute, Singapore.
2001-2003, Project Leader, Grid Biology, BioInformaics Institute, Singapore.
2000-2001, Project Manager, Intoto Inc, CA, USA.
1995-2000, Senior Software Engineer, ISS/KRDL, Singapore.
1989-1995, Member Technical Staff, C-DAC, Pune, India.
1986-1989, Technical Specialist, Artificial Intelligence, Zenith Computers, India.
1983-1986, R&D Manager, Foresight Systems Ltd., New Delhi, India.
HONORS & AWARDS:
2005 Citation in Yearly Comments 2004 of International Microbiology as a new concept in the history of microbial genomics.
1997 - Visiting Scientist, Media Laboratory, MIT, Cambridge, MA.
1994 - Peer Review award in C-DAC’s Application Development Programme.
1992 - UNDP fellowship award to visit Laboratory for Computer Science, MIT
1991 - UNDP fellowship award to visit, University of Bristol.UK
PROFESSIONAL ACTIVITIES:
2005, Commissioned speaker (invited) for Henry Stewart’s online video presentation for
"Using Bioinformatics in the Exploration of Genetic Diversity"
2005 onwards - Steering committee, PRAGMA (Pacific Rim Applications and Grid Middleware Assembly).
2005 - Judge for Asia Pacific BioInformatics Conference, Poster Session, Singapore.
2001 - co-chair, PRAGMA, Resource and Applications Committee.
2005 - Paper setter (invited) for BINC (BioInformatics National Certification Examination), India.
JOURNAL PUBLICATIONS (2004-2006)
[16 published (15 PubMed Indexed)]
1. Sakharkar KR., Sakharkar MK., Chow VT (2006) Gene fusion Making the ends meet.,
Antonie van Leeuwenhoek International Journal of General and Molecular Microbiology,
March 16.
2. Sakharkar KR, Sakharkar MK, Cymbeline TC, Chow VT, Shazib Pervaiz (2006) Functional
and evolutionary analyses on expressed intronless genes in the mouse genome, FEBS letter,
580 :1472-1478.
3. Sakharkar KR., Clement MV, Chow VT, Pervaiz S.(2006) Apoptosis Gene Information
System AGIS, Frontiers in BioScience, 11:1814-1817.
4. Sakharkar MK, Chaturvedi I., Chow VT, sakharkar KR (2005) u-Genome: A database on
Genome Design in Unicellular genomes, In Silico Biology 5, 0055.
5. Sakharkar KR and Chow VT (2005) Strategies for genome reduction in Obligatory
Intracellular parasites, Genome Informatics 16(2): 69-75
6. Sakharkar MK , Kangueane P, Bagavathi SP, Chow VT, Sorscher E, Sakharkar KR and
Hill A. (2005). Human genome from pieces to patterns, Frontiers in BioScience. 10,
2576-2584.
7. Sakharkar MK, Bagavathi SP, Sakharkar KR, Kangueane P (2005). An analysis on gene
architecture in Human and Mouse genomes, In Silico Biol., 5, 0032
8. Bagavathi SP, Sakharkar KR, Chow VT, Kangueane P, Sakharkar MK (2005).Intron
Position conservation across eukaryotic lineages in tubullin genes, Frontiers in
BioScience, 10, 2412-2419
9. Sakharkar KR, Chandra Verma and Vincent T.K. Chow, (2004). Comparative study of
overlapping genes in bacteria, with special reference to Rickettsia prowazekii and
Rickettsia conorii, Int J Syst Evol Microbiol., 55, 1205-1209.
10. Sakharkar KR, Sakharkar MK, Chow VT, (2004). A novel genomics approach for the
identification of drug targets in pathogens, with special reference to Pseudomonas
aeruginosa., In Silico Biol., 4, 0028
11. Sakharkar KR., Dhar PK, Chow.VT. , (2004). Genome compaction in prokaryotic
obligatory intracellular parasites of humans: a comparative analysis, Int J Syst Evol
Microbiol. , 54, 1937-1941.
12. Sakharkar KR, Chow VT. , (2004). PPD - Proteome Profile Database. , In Silico Biol., 4,
0019.
13. Dhar P, Meng TC, Somani S, Ye L, Sairam A, Chitre M, Hao Z, Sakharkar KR, (2004).
Cellware--a multi-algorithmic software for computational systems biology., Bioinformatics., 22, 1319-1321.
14. Sakharkar KR, Chow VT., (2004). Exploring genome architecture through GOV a WWWbased
gene order visualizer, Bioinformatics. , 20, 984-985
15. Pawan Dhar, Tan Chee Meng, Sandeep Somani, Li Ye, Sakharkar KR, Arun Krishnan,
Azmi B.M.Ridwan, Mandar Chitre, Zhu Hao, (2004). Grid Cellware: The first Gridenabled
tool for modeling and simulating cellular processes, Bioinformatics, 21, 1284-1287.
16. Sakharkar KR, Chandra Verma, Chow VT, (2004). Rapid drug target identification in
microbial genomes an inSilico approach with special reference to Salmonella
species. Advances in Bioinformatics and its Applications, World Scientific Publishing Co.
(Book Chapter)
17. Sakharkar KR., Pervaiz S.(2005) Apoptosis Gene Information System AGIS, (AACR,
Jan 26-30, 2005, Waikoloa, Hawaii).